Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073265 | 0.89 | CYP19A1 (0.43) | AKR1C3AKR1C2MAPTELANECYP19A1 | |
| SCHEMBL8073356 | 0.84 | AKR1C3 (0.47) | AKR1C3AKR1C2MAPTRAF1CYP19A1 | |
| SCHEMBL8071414 | 0.83 | MAPT (0.42) | AKR1C3MAPTPTGER4ATMCYP19A1 | |
| SCHEMBL7824961 | 0.76 | CYP19A1 (0.46) | AKR1C3MAPTRAF1CYP19A1 | |
| SCHEMBL7827515 | 0.73 | KMT2A (0.42) | AKR1C3MAPTPTGER4CYP19A1 | |
| SCHEMBL7824962 | 0.73 | AKR1C3 (0.51) | AKR1C3MAPTCYP19A1 | |
| SCHEMBL7816227 | 0.72 | UCHL1 (0.42) | AKR1C3MAPTPTGER4CYP19A1 | |
| SCHEMBL7823440 | 0.71 | UCHL1 (0.41) | AKR1C3MAPTPTGER4CYP19A1 | |
| SCHEMBL8058108 | 0.71 | CYP19A1 (0.43) | MAPTCYP19A1 | |
| SCHEMBL8067988 | 0.71 | MKNK2 (0.43) | AKR1C3AKR1C2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |