Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824961 | 0.89 | CYP19A1 (0.46) | AKR1C3CYP19A1MAPTALDH1A1LMNA | |
| SCHEMBL8068909 | 0.84 | AKR1C3 (0.46) | AKR1C3AKR1C2CYP19A1MAPTRAF1 | |
| SCHEMBL8073265 | 0.83 | CYP19A1 (0.43) | AKR1C3AKR1C2CYP19A1MAPTKDM4E | |
| SCHEMBL8068083 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2CYP19A1MAPTKDM4E | |
| SCHEMBL8073566 | 0.82 | CASP3 (0.44) | AKR1C3CYP19A1MAPTMEN1LMNA | |
| SCHEMBL7824962 | 0.81 | AKR1C3 (0.51) | AKR1C3CYP19A1MAPTMEN1ALDH1A1 | |
| SCHEMBL7828177 | 0.81 | AKR1C3 (0.47) | AKR1C3MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL8057396 | 0.76 | CYP19A1 (0.45) | AKR1C3CYP19A1MAPTMEN1LMNA | |
| SCHEMBL8067025 | 0.76 | AKR1C3 (0.48) | AKR1C3AKR1C2CYP19A1MAPTKDM4E | |
| SCHEMBL7828659 | 0.76 | KDM4E (0.47) | AKR1C3CYP19A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |