Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136100 | 0.74 | CYP24A1 (0.32) | CYP24A1 | |
| SCHEMBL6702689 | 0.74 | AR (0.31) | ALDH1A1 | |
| SCHEMBL6701853 | 0.69 | ALDH1A1 (0.32) | ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL104783 | 0.69 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SIGMAR1TDP1 | |
| SCHEMBL10958618 | 0.69 | CYP2D6 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL5809886 | 0.69 | HIF1A (0.48) | CYP24A1ALDH1A1 | |
| SCHEMBL15229803 | 0.68 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3SIGMAR1FDPS | |
| SCHEMBL2443506 | 0.67 | FDPS (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL8069568 | 0.67 | RIPK1 (0.37) | ALDH1A1 | |
| SCHEMBL6203856 | 0.66 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |