SCHEMBL8069592

SCHEMBL8069592

Cc1ccc(COc2ccc(C(=O)O)c(O)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.62
MAOA P21397 4/20 0.59
PARP10 Q53GL7 1/20 0.54
XDH P47989 1/20 0.52
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
MCL1 Q07820 1/20 0.51
TP53 P04637 1/20 0.50
NR1H4 Q96RI1 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16704452 0.90 MAOB (0.60) MAOBMAOAPARP10ALDH1A1MAPT
SCHEMBL8941559 0.89 MAOB (0.63) MAOBMAOAALDH1A1MCL1
SCHEMBL13978183 0.88 RXRA (0.63) MAOBMAOAXDHMAPTMCL1
SCHEMBL9303625 0.88 LMNA (0.53) MAOBMAOAALDH1A1MAPTMAPK1
SCHEMBL8654378 0.87 XDH (0.49) MAOBMAOAXDHMCL1
SCHEMBL8067308 0.86 PPARD (0.56) MAOBXDHALDH1A1MAPTTP53
SCHEMBL1519064 0.86 MAOB (0.77) MAOBMAOAALDH1A1MCL1
SCHEMBL23812253 0.85 RXRA (0.63) MAOBMAOAMCL1
SCHEMBL3296065 0.85 MAOB (0.76) MAOBMAOAPARP10XDHMCL1
SCHEMBL3298441 0.85 MAOB (0.76) MAOBMAOAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0219302-B2 Recording materials FUJI PHOTO FILM CO LTD (JP) 2000-06-28 EP disclosed
US-4771034-A LEUCO DYE, SALICYCLIC ACID DERIVATIVE AS ELECTRON ACCEPTOR FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
EP-0219302-A2 Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1987-04-22 EP disclosed