Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569510 | 0.84 | ALOX15 (0.47) | MAPTALDH1A1ELANEGAAHSP90AA1 | |
| SCHEMBL237447 | 0.80 | CES2 (0.50) | MAPTALDH1A1ELANEL3MBTL1HSD17B10 | |
| SCHEMBL329955 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1ELANEGAAHSP90AA1 | |
| SCHEMBL4065601 | 0.80 | TDP1 (0.42) | MAPTELANEL3MBTL1HSD17B10ATM | |
| Diphenyl Ethanedioat SCHEMBL27942895 | 0.79 | ELANE (0.53) | MAPTALDH1A1ELANEGAAHSP90AA1 | |
| Water SCHEMBL27685948 | 0.78 | TDP1 (0.41) | MAPTELANEL3MBTL1CYP1A2HSD17B10 | |
| SCHEMBL4092894 | 0.78 | PRSS1 (0.39) | L3MBTL1HSD17B10ATMTDP1 | |
| SCHEMBL58882 | 0.78 | TDP1 (0.44) | MAPTALDH1A1ELANEL3MBTL1HSD17B10 | |
| SCHEMBL9395495 | 0.77 | ELANE (0.52) | MAPTALDH1A1ELANEGAAHSP90AA1 | |
| SCHEMBL43236 | 0.77 | ELANE (0.52) | MAPTALDH1A1ELANEGAAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620857-B1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LTD (GB) | 2000-08-02 | — | — | EP | disclosed |
| US-5686275-A | LACTATE DEHYDROGENASE | GENZYME LTD. (GB) | 1997-11-11 | — | — | US | disclosed |
| EP-0620857-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | Genzyme Limited (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993013215-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LIMITED (GB) | 1993-07-08 | — | — | WO | disclosed |