Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079129 | 0.92 | THRA (0.44) | CSNK2A1PLAUTHRATHRBMAPT | |
| SCHEMBL8069740 | 0.75 | CSNK2A1 (0.41) | CSNK2A1PLAUMAPTHPGDMAPK1 | |
| SCHEMBL3119032 | 0.74 | CSNK2A1 (0.47) | CSNK2A1PLAUTHRBHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3110560 | 0.73 | CSNK2A1 (0.49) | CSNK2A1HPGDGLASMN1; SMN2POLB | |
| SCHEMBL15301623 | 0.72 | SPIN1 (0.38) | CSNK2A1THRATHRBTDP1 | |
| SCHEMBL19549570 | 0.72 | SPIN1 (0.38) | CSNK2A1THRATHRBTDP1 | |
| SCHEMBL6943761 | 0.70 | KDM4E (0.48) | CSNK2A1SMN1; SMN2KMT2A | |
| SCHEMBL8408909 | 0.70 | ALOX5 (0.39) | PLAUTHRATHRBMAPTHPGD | |
| Hydrochloric Acid SCHEMBL3113761 | 0.69 | KDM4E (0.47) | CSNK2A1SMN1; SMN2KMT2A | |
| SCHEMBL10602998 | 0.68 | SCN4A (0.50) | PLAUMAPTHPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |