Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079092 | 0.93 | LMNA (0.44) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8077514 | 0.92 | LMNA (0.43) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8077558 | 0.89 | LMNA (0.44) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8079095 | 0.89 | LMNA (0.40) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8077593 | 0.87 | RAB9A (0.40) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8082210 | 0.87 | RAB9A (0.39) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8079112 | 0.87 | LMNA (0.56) | LMNARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8079200 | 0.86 | LMNA (0.40) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8069905 | 0.86 | LMNA (0.43) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8083894 | 0.86 | LMNA (0.40) | LMNARAB9ANPC1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |