Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | TLR3 | O15455 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876216 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL481982 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL8069838 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL8882171 | 0.79 | ODC1 (0.46) | HIF1AEPAS1ODC1 | |
| SCHEMBL11158278 | 0.77 | TLR3 (0.47) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL8075086 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL13476117 | 0.74 | TLR3 (0.47) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL30065854 | 0.71 | ODC1 (0.44) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL30523681 | 0.71 | CA12 (0.46) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL506743 | 0.71 | CA12 (0.46) | ALDH1A1HPGDCYP3A4TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071953-A | Sulfonamide-substituted chromans, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-06-06 | — | — | US | disclosed |