Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074018 | 1.00 | FPR2 (0.57) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8072202 | 1.00 | FPR2 (0.57) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8074038 | 0.92 | FPR2 (0.55) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8074041 | 0.92 | FPR2 (0.55) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8067627 | 0.90 | FPR2 (0.56) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8067629 | 0.90 | FPR2 (0.56) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8073834 | 0.89 | RAB9A (0.62) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8058666 | 0.89 | FPR2 (0.59) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL9125880 | 0.89 | UTS2R (0.57) | FPR2EPHX2RAB9ANPC1MEN1 | |
| SCHEMBL8073835 | 0.89 | RAB9A (0.62) | FPR2EPHX2RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |