Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 7/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8075315 | 0.88 | SLC9A1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8075312 | 0.87 | PRNP (0.35) | PRNPRXFP1NPSR1MAPK10RAB9A | |
| SCHEMBL8070681 | 0.86 | MAPT (0.42) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8070783 | 0.83 | PTPN1 (0.44) | RAB9AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL8059458 | 0.77 | GPBAR1 (0.50) | GPBAR1CYSLTR1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL8075101 | 0.74 | SLC9A1 (0.41) | — | |
| SCHEMBL7995261 | 0.73 | TTR (0.61) | NPSR1ALDH1A1TTR | |
| Hydrochloric Acid SCHEMBL8075097 | 0.73 | SMN1; SMN2 (0.39) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8070138 | 0.72 | CA1 (0.40) | RAB9AMAPT | |
| SCHEMBL8073502 | 0.72 | TTR (0.51) | NPSR1ALDH1A1MAPTTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |