Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8059727 | 0.85 | HDAC8 (0.39) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL8059524 | 0.83 | KDM4E (0.50) | — | |
| SCHEMBL8070326 | 0.81 | ALDH1A1 (0.44) | — | |
| SCHEMBL7995261 | 0.77 | TTR (0.61) | — | |
| SCHEMBL8073882 | 0.77 | GAA (0.39) | — | |
| SCHEMBL8070146 | 0.77 | PRNP (0.39) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL8073502 | 0.76 | TTR (0.51) | — | |
| SCHEMBL8068695 | 0.74 | ADRA1A (0.42) | — | |
| SCHEMBL8815218 | 0.73 | NR4A2 (0.58) | — | |
| SCHEMBL8059681 | 0.72 | TTR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |