Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8070138 | 0.88 | CA1 (0.40) | MAPTCA1CA2CA7CA13 | |
| Hydrochloric Acid SCHEMBL8070136 | 0.87 | MAPT (0.40) | KMT2AALDH1A1HPGDMAPTCA1 | |
| SCHEMBL8446364 | 0.86 | CA1 (0.55) | PTPN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8070146 | 0.83 | PRNP (0.39) | KMT2AALDH1A1KDM4ETHRBMAPT | |
| SCHEMBL8070681 | 0.81 | MAPT (0.42) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL8070326 | 0.77 | ALDH1A1 (0.44) | KMT2AALDH1A1KDM4ETHRBHPGD | |
| SCHEMBL8446359 | 0.74 | CA1 (0.51) | PTPN1KMT2AALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL8444771 | 0.74 | CA1 (0.51) | PTPN1KMT2AALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL8075315 | 0.72 | SLC9A1 (0.39) | — | |
| SCHEMBL7995261 | 0.72 | TTR (0.61) | ALDH1A1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | disclosed |