Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744951 | 0.87 | HTR2A (0.50) | ALDH1A1MEN1KMT2AMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL27486308 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4107880 | 0.79 | CHRM2 (0.50) | KDM4EALDH1A1TDP1MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL8197750 | 0.79 | CHRM2 (0.50) | KDM4EALDH1A1TDP1MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL29269181 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2838056 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5168468 | 0.77 | CHRM2 (0.51) | ALDH1A1MEN1KMT2AMAPK1HTR2A | |
| SCHEMBL12970937 | 0.77 | CHRM2 (0.51) | ALDH1A1MEN1KMT2AMAPK1HTR2A | |
| Styrene SCHEMBL10902441 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL387947 | 0.76 | ALDH1A1 (0.71) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696518-B1 | Heat sensitive ink sheet and image forming method | FUJI PHOTO FILM CO LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| EP-0730978-B1 | Image-receiving sheet material, method for forming transfer image and laminate | FUJI PHOTO FILM CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0698500-B1 | Image receiving sheet and image forming method | FUJI PHOTO FILM CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5629129-A | Heat sensitive ink sheet and image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| US-5607809-A | SUPPORTS WITH MULTILAYER IMAGE RECEIVER SHEETS OF CATIONIC POLYMER AND BUTYRAL RESINS | FUJI PHOTO FILM CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5576140-A | MODIFIED POLYVINYL ACETAL | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0730978-A2 | Image-receiving sheet material, method for forming transfer image and laminate | FUJI PHOTO FILM CO., LTD. (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0698500-A1 | Image receiving sheet and image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-28 | — | — | EP | disclosed |
| EP-0696518-A1 | Heat sensitive ink sheet and image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5104778-A | Layer containing anionic dye, cationic polymer mordant, and gelatin | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4948711-A | FIXING SOLUTION CONTAINING A CATIONIC ADDITION POLYMER TO RMOVE IODIDE IONS IN HIGH SPEED CONTINUOUS PROCESSING; EFFICIENCY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |