Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731743 | 0.82 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3125256 | 0.82 | PIK3CG (0.61) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL22230597 | 0.82 | SLC40A1 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGEGFR | |
| SCHEMBL790162 | 0.80 | ALDH1A1 (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL15651564 | 0.80 | MCL1 (0.47) | GAAGFERAPOBEC3GPIK3CDPIK3CA | |
| SCHEMBL16234987 | 0.79 | S100A9 (0.56) | GAAGFERAPOBEC3GERBB2HSP90AA1 | |
| SCHEMBL358926 | 0.79 | PIK3CG (0.63) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL21512962 | 0.79 | MAPT (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL29969482 | 0.79 | MAPT (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL740383 | 0.77 | LMNA (0.53) | GAAPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |