Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445397 | 0.90 | MAOA (0.48) | MAOAMAOBTAAR1TSHRLMNA | |
| SCHEMBL1361875 | 0.87 | TSHR (0.58) | MAOAMAOBTAAR1TSHRLMNA | |
| SCHEMBL6583082 | 0.83 | MAOA (0.50) | MAOAMAOBTAAR1TSHRLMNA | |
| SCHEMBL27690381 | 0.81 | LMNA (0.54) | LMNADPP4AKR1C1SMN1; SMN2L3MBTL1 | |
| SCHEMBL625584 | 0.79 | HSD11B1 (0.64) | TSHRLMNADPP4AKR1C1SMN1; SMN2 | |
| SCHEMBL977926 | 0.79 | HSD11B1 (0.69) | TSHRLMNADPP4AKR1C1SMN1; SMN2 | |
| SCHEMBL2444780 | 0.79 | MAOA (0.46) | MAOAMAOBTAAR1TSHRLMNA | |
| SCHEMBL2439823 | 0.79 | LMNA (0.44) | TSHRLMNADPP4AKR1C1SMN1; SMN2 | |
| SCHEMBL5365797 | 0.78 | HSD11B1 (0.72) | TSHRLMNADPP4AKR1C1SMN1; SMN2 | |
| SCHEMBL6554492 | 0.76 | LMNA (0.49) | MAOAMAOBTAAR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024135-A1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 2000-08-02 | — | — | EP | disclosed |