Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078598 | 0.83 | PTGER4 (0.48) | PTGER1GLRA1PTGER4PTGER3PTGER2 | |
| SCHEMBL28877496 | 0.82 | ALDH1A1 (0.49) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL1169607 | 0.82 | TSHR (0.51) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL15716510 | 0.82 | ALDH1A1 (0.58) | PTGER1ALDH1A1KMT2AMEN1CTSV | |
| SCHEMBL4636545 | 0.82 | PTGER4 (0.51) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL128058 | 0.80 | GLRA1 (0.57) | PTGER1GLRA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9125830 | 0.78 | PTGER4 (0.54) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL8980650 | 0.78 | MAOB (0.54) | PTGER1ALDH1A1KMT2AMEN1CTSV | |
| SCHEMBL1396290 | 0.78 | ALDH1A1 (0.57) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL8545823 | 0.77 | PTGER1 (0.55) | PTGER1ALDH1A1KMT2AMEN1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083987-A | 4-AMINO DERIVATIVE SUBSTITUTED PHENYLDIALKYLAMINE, USEFUL AS LIPID PEROXIDATION INHIBITOR | SHISEIDO CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |