Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194096 | 0.91 | PPARG (0.70) | PPARGEDNRAAGTR1AGTR2 | |
| SCHEMBL9443092 | 0.89 | PPARG (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL27528971 | 0.88 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL9847764 | 0.85 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL9442986 | 0.85 | EDNRA (0.54) | PPARGEDNRAAGTR1AGTR2 | |
| SCHEMBL9847780 | 0.84 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL9200218 | 0.84 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL9198282 | 0.83 | PPARG (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL8563884 | 0.83 | PPARG (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL7177667 | 0.83 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |