SCHEMBL8070952

SCHEMBL8070952

C=CCCc1ccc(OCCC)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SLC5A1 P13866 1/20 0.48
SLC5A2 P31639 1/20 0.48
ACACB O00763 1/20 0.44
LTA4H P09960 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 1/20 0.44
HRH3 Q9Y5N1 2/20 0.43
ALDH1A1 P00352 3/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
MAPT P10636 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072074 0.93 ALDH1A1 (0.49) LMNAL3MBTL1MEN1KMT2ALTA4H
SCHEMBL8062365 0.90 L3MBTL1 (0.51) LMNAL3MBTL1MEN1KMT2ASLC5A1
SCHEMBL8072896 0.88 LMNA (0.50) LMNAL3MBTL1MEN1KMT2ASLC5A1
SCHEMBL6142219 0.88 ACACB (0.52) LMNAL3MBTL1MEN1KMT2ASLC5A1
SCHEMBL8076261 0.87 MEN1 (0.51) LMNAL3MBTL1MEN1KMT2ATHRB
SCHEMBL8078008 0.87 MEN1 (0.51) LMNAL3MBTL1MEN1KMT2ATHRB
SCHEMBL8072816 0.87 MEN1 (0.51) LMNAL3MBTL1MEN1KMT2ATHRB
SCHEMBL8071480 0.87 MEN1 (0.51) LMNAL3MBTL1MEN1KMT2ATHRB
SCHEMBL10335128 0.85 ACACB (0.49) LMNAL3MBTL1MEN1KMT2AACACB
SCHEMBL8073008 0.85 NQO1 (0.54) LMNAL3MBTL1SLC5A1SLC5A2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063940-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-16 US disclosed
US-5637736-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed