SCHEMBL8070982

SCHEMBL8070982

Cc1ccccc1C1(O)Cc2ccccc2C1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
OPRK1 P41145 1/20 0.46
OPRL1 P41146 1/20 0.46
GRIN2B Q13224 10/20 0.42
HDAC4 P56524 1/20 0.40
HDAC9 Q9UKV0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29060516 0.80 OPRM1 (0.59) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL27625085 0.77 OPRM1 (0.56) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL28994161 0.77 OPRM1 (0.56) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL29273456 0.77 OPRM1 (0.47) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL17679906 0.75 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL5349864 0.75 OPRM1 (0.54) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL5866512 0.75 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL17888234 0.75 OPRM1 (0.62) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL2270935 0.72 SIGMAR1 (0.62) OPRM1OPRD1OPRK1OPRL1GRIN2B
SCHEMBL12862966 0.72 OPRM1 (0.51) OPRM1OPRD1OPRK1OPRL1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745099-B1 REACTOR BLEND POLYPROPYLENE AND PROCESS FOR THE PREPARATION THEREOF MONTELL TECHNOLOGY COMPANY BV (NL) 2000-09-13 EP disclosed
US-6107431-A CATALYTIC POLYMERIZATION OF POLYPROPYLENE THERMOPLASTIC ELASTOMER USING ALUMOXANE-METALLOCENE DERIVATIVE CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 2000-08-22 US disclosed
US-5747621-A CATALYTIC ADDITION POLYMERIZATION MONTELL TECHNOLOGY COMPANY BV (NL) 1998-05-05 US disclosed
CN-1147822-A Reactor blend polypropylene, process for the preparation thereof and process for preparing metallocene ligands MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-16 CN disclosed
EP-0745099-A1 REACTOR BLEND POLYPROPYLENE, PROCESS FOR THE PREPARATION THEREOF AND PROCESS FOR PREPARING METALLOCENE LIGANDS Montell Technology Company bv (NL) 1996-12-04 EP disclosed
WO-1996020225-A2 REACTOR BLEND POLYPROPYLENE, PROCESS FOR THE PREPARATION THEREOF AND PROCESS FOR PREPARING METALLOCENE LIGANDS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1996-07-04 WO disclosed