Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.31 |
| ▸ | GNPAT | O15228 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277311 | 0.81 | EPHX2 (0.45) | EPHX2C3AR1SMN1; SMN2CPB2CHRNB2 | |
| SCHEMBL10277291 | 0.80 | EPHX2 (0.47) | EPHX2C3AR1SMN1; SMN2CPB2CHRNB2 | |
| SCHEMBL27572862 | 0.79 | EED (0.44) | EPHX2C3AR1SMN1; SMN2CPB2 | |
| SCHEMBL29577658 | 0.79 | EED (0.44) | EPHX2C3AR1SMN1; SMN2CPB2 | |
| SCHEMBL27572870 | 0.79 | EED (0.44) | EPHX2C3AR1SMN1; SMN2CPB2 | |
| Acetic Acid SCHEMBL22639109 | 0.76 | EED (0.44) | EPHX2SMN1; SMN2CPB2 | |
| Acetic Acid SCHEMBL22639110 | 0.76 | EED (0.44) | EPHX2SMN1; SMN2CPB2 | |
| SCHEMBL6561158 | 0.74 | GRIN1 (0.44) | EPHX2SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7897054 | 0.73 | EPHX2 (0.44) | EPHX2C3AR1SMN1; SMN2CPB2CHRNB2 | |
| SCHEMBL17104387 | 0.73 | GRIN1 (0.45) | EPHX2SMN1; SMN2CPB2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017664-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015490-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | claimed |