Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 13/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953252 | 0.90 | PDGFRB (0.58) | ALPLPDGFRBKDRKMT2A | |
| SCHEMBL14247769 | 0.83 | ALPL (0.51) | ALPLPDGFRBKDRALDH1A1KMT2A | |
| SCHEMBL14247329 | 0.81 | ALPL (0.47) | ALPLPDGFRBKDRKMT2A | |
| SCHEMBL14247561 | 0.80 | PDGFRB (0.45) | ALPLPDGFRBKDRKMT2A | |
| SCHEMBL798423 | 0.77 | ALPL (0.76) | ALPLPDGFRBKDRALDH1A1KMT2A | |
| SCHEMBL9952995 | 0.77 | LMNA (0.49) | ALPLPDGFRBKDRKMT2ALMNA | |
| SCHEMBL9952627 | 0.76 | ALPL (0.56) | ALPLPDGFRBKDRALDH1A1LMNA | |
| SCHEMBL14247605 | 0.76 | PDGFRB (0.48) | ALPLPDGFRBKDRKMT2ALMNA | |
| SCHEMBL729722 | 0.76 | PDGFRB (0.45) | ALPLPDGFRBKDR | |
| SCHEMBL15882692 | 0.76 | PDGFRB (0.45) | ALPLPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |