Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324227 | 0.78 | CA12 (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9284377 | 0.75 | ALDH1A1 (0.58) | ALOX15ALDH1A1KDM4EHBBHSD17B10 | |
| SCHEMBL10661265 | 0.75 | CA12 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL4299181 | 0.74 | CA12 (0.43) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL3227580 | 0.74 | CA12 (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1CA12 | |
| SCHEMBL11874433 | 0.74 | ACHE (0.38) | ALDH1A1KDM4ESMN1; SMN2CA12BRD4 | |
| SCHEMBL29433205 | 0.73 | TDP1 (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28498048 | 0.72 | CA12 (0.41) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL30704385 | 0.72 | CA12 (0.41) | ALDH1A1KDM4EKMT2AMEN1CA12 | |
| SCHEMBL30925613 | 0.72 | CA12 (0.41) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133264-A | Carbostyril derivatives for inhibiting skin erythema and/or skin pigmentation | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |