Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576533 | 0.85 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL7966259 | 0.82 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7571057 | 0.76 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL8086064 | 0.73 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL8732695 | 0.70 | P2RX7 (0.58) | P2RX7SLC6A9 | |
| SCHEMBL24515745 | 0.69 | P2RX7 (0.60) | P2RX7SLC6A9 | |
| SCHEMBL9017627 | 0.69 | MAPK14 (0.55) | P2RX7 | |
| SCHEMBL8932345 | 0.67 | P2RX7 (0.57) | P2RX7SLC6A9 | |
| SCHEMBL7690936 | 0.67 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL24209849 | 0.67 | JAK1 (0.59) | P2RX7SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-A1 | ADAMANTANE DERIVATIVES | AstraZeneca UK Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029661-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |