SCHEMBL8932345

SCHEMBL8932345

CCNC(=O)c1c(N)cccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.57
JAK1 P23458 2/20 0.54
SLC6A9 P48067 13/20 0.50
ALDH1A1 P00352 2/20 0.49
HPGD P15428 1/20 0.49
PRKCZ Q05513 1/20 0.46
JAK2 O60674 1/20 0.44
TYK2 P29597 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4155966 0.88 ALDH1A1 (0.61) P2RX7JAK1ALDH1A1HPGDPRKCZ
SCHEMBL8732695 0.87 P2RX7 (0.58) P2RX7JAK1SLC6A9ALDH1A1HPGD
SCHEMBL24209849 0.82 JAK1 (0.59) P2RX7JAK1SLC6A9ALDH1A1HPGD
SCHEMBL7457606 0.81 JAK1 (0.58) P2RX7JAK1SLC6A9ALDH1A1HPGD
SCHEMBL15518786 0.80 KMT2A (0.40) P2RX7ALDH1A1HPGDPRKCZ
SCHEMBL8424563 0.80 NPC1 (0.46) HPGDPOLB
SCHEMBL30739840 0.80 PRKCZ (0.49) P2RX7JAK1SLC6A9ALDH1A1HPGD
SCHEMBL20050668 0.80 PRKCZ (0.49) P2RX7JAK1SLC6A9ALDH1A1HPGD
SCHEMBL5022118 0.80 HPGD (0.59) JAK1HPGDJAK2TYK2POLB
SCHEMBL9017625 0.80 PRKCZ (0.49) P2RX7ALDH1A1HPGDPRKCZPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749416-A1 SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1996-12-27 EP disclosed
US-5482974-A AMINO OR ETHER BENZAMIDES MONSANTO COMPANY (US) 1996-01-09 US disclosed
WO-1995024380-A1 SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1995-09-14 WO disclosed