Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18193727 | 0.86 | GSR (0.44) | GSRPTGS2ENPP2AKR1C3 | |
| SCHEMBL28427675 | 0.83 | GSK3B (0.53) | GSRPTGS2ENPP2AKR1C3 | |
| SCHEMBL7481806 | 0.81 | ENPP2 (0.47) | GSRPTGS2ENPP2AKR1C3 | |
| SCHEMBL5502450 | 0.80 | TDP1 (0.46) | AKR1C3 | |
| SCHEMBL3110619 | 0.79 | GSK3B (0.48) | — | |
| SCHEMBL3033043 | 0.79 | SLC6A2 (0.47) | — | |
| SCHEMBL11835508 | 0.78 | HPGD (0.56) | PTGS2 | |
| SCHEMBL7878318 | 0.78 | HTT (0.51) | — | |
| SCHEMBL2702007 | 0.78 | PTPN1 (0.47) | — | |
| SCHEMBL4421773 | 0.78 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | disclosed |