Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071975 | 0.91 | ADRA1A (0.56) | ADRA1AADRA1B | |
| SCHEMBL8076826 | 0.85 | ADRA1A (0.56) | ADRA1AADRA1BADRA1D | |
| SCHEMBL8077026 | 0.77 | ADRA1A (0.60) | ADRA1AADRA1BADRA1D | |
| SCHEMBL8061075 | 0.76 | EHMT2 (0.48) | ADRA1AADRA1B | |
| SCHEMBL8070173 | 0.76 | HCAR3 (0.55) | — | |
| SCHEMBL8071911 | 0.75 | ADRA1A (0.62) | ADRA1AADRA1B | |
| SCHEMBL8071651 | 0.75 | ADRA1A (0.57) | ADRA1AADRA1BADRA1D | |
| SCHEMBL22206324 | 0.74 | ADRA1A (0.58) | ADRA1AADRA1BADRA1D | |
| SCHEMBL15321173 | 0.74 | HCAR3 (0.68) | — | |
| SCHEMBL32660016 | 0.74 | HCAR3 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156758-A | Antibacterial quinazoline compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |