Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077026 | 0.92 | ADRA1A (0.60) | ADRA1AADRA1BADRA1D | |
| SCHEMBL8061075 | 0.90 | EHMT2 (0.48) | ADRA1AADRA1B | |
| SCHEMBL8071911 | 0.88 | ADRA1A (0.62) | ADRA1AADRA1B | |
| SCHEMBL8070274 | 0.86 | CCR4 (0.52) | — | |
| SCHEMBL8071621 | 0.85 | ABCG2 (0.48) | ADRA1AADRA1B | |
| SCHEMBL8071822 | 0.85 | ADRA1A (0.49) | ADRA1AADRA1BADRA1D | |
| SCHEMBL8071618 | 0.84 | DNMT1 (0.45) | — | |
| SCHEMBL8071876 | 0.83 | MGLL (0.46) | — | |
| SCHEMBL8071651 | 0.80 | ADRA1A (0.57) | ADRA1AADRA1BADRA1D | |
| SCHEMBL8071748 | 0.79 | ADRA1A (0.60) | ADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156758-A | Antibacterial quinazoline compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |