Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8071885

CCCC(=O)NC1CCCC(C)(C)C1.CCCC(=O)N[Ti+2].[Cl-].[Cl-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.37
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
EPHX2 P34913 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.35
HDAC3 O15379 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC10 Q969S8 2/20 0.34
HDAC11 Q96DB2 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
HSD11B1 P28845 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067398 0.92 SMN1; SMN2 (0.37) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8069069 0.86 MTNR1A (0.34) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8068497 0.85 SMN1; SMN2 (0.37) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8068022 0.84 SMN1; SMN2 (0.36) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8068140 0.84 SMN1; SMN2 (0.36) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8071519 0.83 SMN1; SMN2 (0.38) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8068512 0.82 SMN1; SMN2 (0.38) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
Hydrochloric Acid SCHEMBL8073534 0.81 SMN1; SMN2 (0.36) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
SCHEMBL9681 0.79 SMN1; SMN2 (0.39) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2
SCHEMBL8071405 0.79 SMN1; SMN2 (0.35) SMN1; SMN2GAAMTNR1AMTNR1BEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127496-A POLYMERIZING OLEFINICALLY UNSATURATED COMPOUNDS IN PRESENCE OF METALLOCENE CATALYST SYSTEM CONTAINING A COMPOUND CAPABLE OF FORMING METALLOCENIUM IONS BASF AKTIENGESELLSCHAFT (DE) 2000-10-03 US disclosed
US-6077965-A Metal complexes with an adamantane-like structure BASF AKTIENGESELLSCHAFT (DE) 2000-06-20 US disclosed