Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066942 | 0.94 | MKNK2 (0.44) | ALDH1A1MKNK2KMT2AHPGDAKR1C3 | |
| SCHEMBL8071430 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KMT2AHPGDAKR1C3AKR1C2 | |
| SCHEMBL8073234 | 0.89 | MEN1 (0.44) | ALDH1A1MKNK2KMT2AHPGDAKR1C3 | |
| SCHEMBL7823983 | 0.87 | LMNA (0.45) | ALDH1A1KMT2AHPGDAKR1C3PTGDR2 | |
| SCHEMBL7816184 | 0.85 | CYP19A1 (0.44) | ALDH1A1KMT2AHPGDMEN1HSD17B10 | |
| SCHEMBL8057450 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MKNK2KMT2AHPGDAKR1C3 | |
| SCHEMBL8067007 | 0.84 | KMT2A (0.45) | ALDH1A1KMT2AHPGDAKR1C3AKR1C2 | |
| SCHEMBL8067988 | 0.83 | MKNK2 (0.43) | ALDH1A1MKNK2KMT2AHPGDAKR1C3 | |
| SCHEMBL8073462 | 0.82 | MKNK2 (0.46) | ALDH1A1MKNK2KMT2AHPGDAKR1C3 | |
| SCHEMBL7831187 | 0.82 | CYP19A1 (0.47) | ALDH1A1HPGDAKR1C3MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |