Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 14/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061294 | 0.85 | PTGS2 (0.52) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL8071781 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL6729582 | 0.80 | PTGS2 (0.44) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL6737317 | 0.79 | PTGS2 (0.43) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL7215571 | 0.79 | PTGS2 (0.62) | PTGS2PTGS1SOS1 | |
| SCHEMBL8061374 | 0.78 | PTGS2 (0.61) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL8071998 | 0.77 | CA12 (0.63) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL6721959 | 0.77 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL6726544 | 0.77 | PTGS2 (0.42) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL8061447 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | claimed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | claimed |
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | disclosed |