Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 15/20 | 0.63 |
| ▸ | CA1 | P00915 | 15/20 | 0.63 |
| ▸ | CA2 | P00918 | 15/20 | 0.63 |
| ▸ | CA9 | Q16790 | 15/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061374 | 0.86 | PTGS2 (0.61) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8061294 | 0.83 | PTGS2 (0.52) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL4622748 | 0.83 | GSK3B (0.47) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL4616213 | 0.83 | GSK3B (0.50) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8061447 | 0.82 | PTGS2 (0.62) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL5674068 | 0.79 | CA12 (0.62) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8071992 | 0.77 | PTGS2 (0.51) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8071781 | 0.77 | PTGS2 (0.48) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL4616451 | 0.75 | KMT2A (0.57) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL677082 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | claimed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | claimed |
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | disclosed |