SCHEMBL8072011

SCHEMBL8072011

CCCC1CCC(C2CCC(c3ccc(OC)c(F)c3F)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39
CYP2C9 P11712 1/20 0.35
DRD2 P14416 2/20 0.35
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
OPRL1 P41146 7/20 0.33
USP30 Q70CQ3 1/20 0.33
PDE5A O76074 1/20 0.33
ACHE P22303 1/20 0.33
HTR4 Q13639 1/20 0.33
HTR2A P28223 1/20 0.33
HTR1A P08908 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18134229 1.00 ALDH1A1 (0.39) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL17614879 0.99 ALDH1A1 (0.38) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL14234681 0.96 ALDH1A1 (0.41) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL17614874 0.94 ALDH1A1 (0.40) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL19985175 0.92 ACHE (0.34) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL8961759 0.92 FPR2 (0.36) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL17736127 0.91 CNR2 (0.34) ALDH1A1MAPTHTTDRD2MEN1
SCHEMBL19985477 0.91 ALDH1A1 (0.38) ALDH1A1MAPTHTTCYP2C9DRD2
SCHEMBL19985213 0.90 MAPT (0.36) ALDH1A1MAPTHTTDRD2MEN1
SCHEMBL19985179 0.90 MAPT (0.36) ALDH1A1MAPTHTTDRD2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113671068-A Method for analyzing environmental pollutant targeting exposure component in blood plasma and application thereof 暨南大学 2021-11-19 CN claimed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-20230323207-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230323207-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-9181480-B2 Liquid crystal composition, liquid crystal display element, and liquid crystal display DIC CORPORATION (JP) 2015-11-10 US disclosed
EP-2883937-A1 LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2015-06-17 EP disclosed
US-20150028256-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC CORPORATION (JP) 2015-01-29 US disclosed
US-20150028256-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC CORPORATION (JP) 2015-01-29 US disclosed
EP-2808376-A1 METHOD FOR PRODUCING COMPOSITION DIC Corporation (JP) 2014-12-03 EP disclosed
US-8148551-B2 Tricyclic aromatics and liquid-crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-04-03 US disclosed
US-8029696-B2 Fused naphthalenes MERCK PATENT GMBH (DE) 2011-10-04 US disclosed
US-20100059711-A1 FUSED NAPHTHALENES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-03-11 US disclosed
US-20090131689-A1 TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2009-05-21 US disclosed
EP-1026142-A1 2,3-DIFLUOROPHENYL DERIVATIVES HAVING NEGATIVE VALUE OF PERMITTIVITY ANISOTROPY, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 ALDH1A1 3448/4885MAPT 1064/4885HTT 4816/4885
US-20090131689-A1 TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM CHRM1, C1S, CHRM2 ALDH1A1 2248/4885MAPT 1097/4885HTT 1579/4885
US-20100059711-A1 FUSED NAPHTHALENES CCNE2, CCNE1, F12 ALDH1A1 1986/4885MAPT 3032/4885HTT 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.