Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290253 | 0.84 | JMJD6 (0.51) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL18760785 | 0.84 | TDP1 (0.56) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL8072052 | 0.79 | LMNA (0.56) | SMN1; SMN2TDP1KMT2APOLBMAPT | |
| SCHEMBL1267682 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2APOLBMEN1NPC1 | |
| SCHEMBL20646162 | 0.75 | GPR52 (0.52) | TDP1KMT2ASLC6A2SLC6A3JMJD6 | |
| SCHEMBL22005632 | 0.73 | TDP1 (0.53) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20154228 | 0.73 | MAPT (0.57) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9374743 | 0.73 | TDP1 (0.66) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL26783213 | 0.73 | TDP1 (0.56) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20776996 | 0.72 | TDP1 (0.51) | SMN1; SMN2TDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757987-B1 | Pyrazole-carboxylic acid derivatives as plant disease control agents | NISSAN CHEMICAL IND LTD (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5817829-A | FUNGICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0757987-A1 | PYRAZOLECARBOXYLIC ACID DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |