Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | KDM6B | O15054 | 1/20 | 0.61 |
| ▸ | KDM5C | P41229 | 1/20 | 0.61 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.61 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172100 | 1.00 | EGLN1 (0.61) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL31474557 | 1.00 | EGLN1 (0.61) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1172512 | 0.97 | EGLN1 (0.64) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL1924688 | 0.86 | LDHA (0.53) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL21174517 | 0.83 | LMNA (0.82) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL26625806 | 0.83 | LMNA (0.82) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL28505622 | 0.83 | LMNA (0.82) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL21044870 | 0.83 | ALDH1A1 (0.67) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL2439884 | 0.83 | ALDH1A1 (0.77) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL7673665 | 0.83 | LDHA (0.57) | EGLN1KDM4EKDM6BKDM5CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |