Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8072098

CCCCCCCCCCCC[N+](C)(C)Cc1cccc(Cl)c1Cl.[Cl-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.43
CHRM2 known ✓ P08172 1/20 0.40
CHRM1 known ✓ P11229 1/20 0.40
CHRM3 known ✓ P20309 1/20 0.40
SLC6A2 known ✓ P23975 1/20 0.40
SLC6A3 known ✓ Q01959 1/20 0.40
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
MAPK1 P28482 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.54
HTT P42858 5/20 0.53
DNM1 Q05193 7/20 0.51
HSP90AA1 P07900 2/20 0.48
RAD52 P43351 2/20 0.48
PSMD14 O00487 1/20 0.48
MMP2 P08253 1/20 0.48
MC4R P32245 1/20 0.48
PLA2G1B P04054 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6576279 1.00 KMT2A (0.54) KMT2AMEN1MAPK1SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL6576294 1.00 KMT2A (0.54) KMT2AMEN1MAPK1SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL6576354 1.00 KMT2A (0.54) KMT2AMEN1MAPK1SMN1; SMN2TP53
SCHEMBL6572362 0.98 DNM1 (0.53) KMT2AMEN1MAPK1SMN1; SMN2TP53
SCHEMBL6543022 0.98 DNM1 (0.53) KMT2AMEN1MAPK1SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL11140883 0.88 KMT2A (0.61) KMT2AMEN1MAPK1SMN1; SMN2TP53
SCHEMBL7132276 0.84 PNMT (0.43) KMT2AMEN1MAPK1SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL7764453 0.82 KMT2A (0.71) KMT2AMEN1MAPK1SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL8720796 0.82 KMT2A (0.71) KMT2AMEN1MAPK1SMN1; SMN2TP53
Hydrochloric Acid SCHEMBL7760973 0.82 KMT2A (0.71) KMT2AMEN1MAPK1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2432323-B1 METHOD FOR PREVENTING AND CONTROLLING BIOFOULING ON MARINE OBJECTS BY CARBONIC ANHYDRASE-CATALYSED RELEASE OF CARBON DIOXIDE ARCHIMEDE R & D S R L (IT) 2014-09-24 EP disclosed
EP-0765331-B1 OXABOROLES AND SALTS THEREOF, AND THEIR USE AS BIOCIDES AVECIA LTD (GB) 2000-08-09 EP disclosed
US-5880188-A PROTECTING MEDIUM SUSCEPTIBLE TO MICROBIAL ATTACK BY TREATING WITH SPECIFIED OXABOROLE COMPOUND ZENECA LIMITED (GB) 1999-03-09 US disclosed
WO-1997011952-A1 FUNGICIDES ZENECA LIMITED (GB) 1997-04-03 WO disclosed
EP-0765331-A1 OXABOROLES AND SALTS THEREOF, AND THEIR USE AS BIOCIDES ZENECA LIMITED (GB) 1997-04-02 EP disclosed
WO-1997000613-A1 COMPOSITION BIOCIDAL ZENECA LIMITED (GB) 1997-01-09 WO disclosed
WO-1995033754-A1 OXABOROLES AND SALTS THEREOF, AND THEIR USE AS BIOCIDES ZENECA LIMITED (GB) 1995-12-14 WO disclosed
US-4126574-A Surfactant-containing aluminosilicates and process HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-11-21 US disclosed