SCHEMBL8072267

SCHEMBL8072267

CCCCCC(C)Oc1ccc(OC(C)=O)cc1OC(C)CCCCC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
KDM4E B2RXH2 1/20 0.42
MAPT P10636 2/20 0.41
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
LTA4H P09960 1/20 0.39
ELANE P08246 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
TSHR P16473 1/20 0.38
PTGS2 P35354 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
FAAH O00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080297 0.96 KDM4E (0.43) ALOX5KDM4EMAPTNPC1LMNA
SCHEMBL8081664 0.90 KDM4E (0.45) ALOX5KDM4EMAPTNPC1LMNA
SCHEMBL8081333 0.85 ALOX5 (0.51) ALOX5KDM4EMAPTLMNAHTT
SCHEMBL8086383 0.84 GPR88 (0.45) ALOX5MAPTLMNAPKMELANE
SCHEMBL8072665 0.84 KDM4E (0.47) KDM4EMAPTNPC1LMNAPKM
SCHEMBL8086396 0.84 ALOX5 (0.52) ALOX5KDM4EMAPTLMNAHTT
SCHEMBL8080238 0.84 ALOX5 (0.52) ALOX5KDM4EMAPTLMNAHTT
SCHEMBL8086558 0.83 ALDH1A1 (0.45) ALOX5KDM4EMAPTLMNAPKM
SCHEMBL8081120 0.83 ALDH1A1 (0.45) ALOX5KDM4EMAPTLMNAPKM
SCHEMBL9296514 0.83 ALDH1A1 (0.45) ALOX5KDM4EMAPTLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed