SCHEMBL8072296

SCHEMBL8072296

CCC(C)COc1cc(OC(C)=O)cc(OCC(C)CC)c1OCC(C)CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
ELANE P08246 2/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
GLA P06280 2/20 0.40
GAA P10253 2/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
FFAR1 O14842 1/20 0.40
TLR8 Q9NR97 1/20 0.37
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
BACE1 P56817 1/20 0.36
GPR88 Q9GZN0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080653 0.79 MAPT (0.50) MAPTHSD17B10MAPK1HTTFFAR1
SCHEMBL8072295 0.77 THRB (0.54) MAPTALDH1A1GAAFFAR1TLR8
SCHEMBL8081325 0.77 FFAR1 (0.57) ELANEMAPTALDH1A1LMNAGAA
SCHEMBL8086416 0.73 ALOX5 (0.43) ALOX5ELANEKDM4EMAPTALDH1A1
SCHEMBL6364978 0.70 PTPN1 (0.47) ALOX5ELANEKDM4EMAPTALDH1A1
SCHEMBL28518652 0.69 ELANE (0.50) ELANEKDM4EALDH1A1HSD17B10TP53
SCHEMBL28518653 0.69 ELANE (0.50) ELANEKDM4EALDH1A1HSD17B10TP53
SCHEMBL10138524 0.68 TSHR (0.44) ALOX5KDM4EMAPTALDH1A1LMNA
SCHEMBL8086442 0.68 ALOX5 (0.45) ALOX5ELANEKDM4EMAPTALDH1A1
SCHEMBL8080300 0.68 POLB (0.41) MAPTHTTGPR88TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed