Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299046 | 0.84 | PRSS1 (0.56) | ACEOPRM1 | |
| SCHEMBL7340883 | 0.84 | PRSS1 (0.56) | ACEOPRM1 | |
| SCHEMBL7299051 | 0.84 | PRSS1 (0.56) | ACEOPRM1 | |
| SCHEMBL5710967 | 0.83 | ACE (0.61) | ACEACE2OPRM1LTA4H | |
| SCHEMBL7280460 | 0.83 | ACE (0.69) | ACEACE2OPRM1 | |
| SCHEMBL7343554 | 0.82 | ACE (0.51) | ACEACE2OPRM1LTA4H | |
| SCHEMBL8250626 | 0.82 | OPRM1 (0.60) | ACEOPRM1 | |
| SCHEMBL6412059 | 0.81 | ACE (0.66) | ACE | |
| SCHEMBL7087290 | 0.81 | ACE (0.66) | ACE | |
| SCHEMBL6412055 | 0.81 | ACE (0.66) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012165-A1 | PROCESS FOR THE PREPARATION OF N-METHYL-D-PHENYLALANYL-N- 1- 3- (AMINOIMINOMETHYL)AMINO]PROPYL]-3,3-DIFLUORO-2-OXOHEXYL]-L-PROLINAMIDE | Aventis Pharmaceuticals Inc. (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1997035874-A1 | PROCESS FOR THE PREPARATION OF N-METHYL-D-PHENYLALANYL-N-[1-[3-[(AMINOIMINOMETHYL)AMINO]PROPYL]-3,3-DIFLUORO-2-OXOHEXYL]-L-PROLINAMIDE | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-02 | — | — | WO | claimed |