Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339534 | 0.86 | F2 (0.54) | ACEF2PRSS1 | |
| SCHEMBL8072498 | 0.82 | ACE (0.57) | ACEOPRM1LTA4HACE2 | |
| SCHEMBL7155123 | 0.82 | TMPRSS11D (0.47) | F2 | |
| SCHEMBL7343558 | 0.81 | DPP4 (0.53) | DPP4OPRM1F2 | |
| SCHEMBL7343548 | 0.81 | DPP4 (0.53) | DPP4OPRM1F2 | |
| SCHEMBL7154243 | 0.81 | TMPRSS11D (0.50) | F2 | |
| SCHEMBL7402728 | 0.80 | ACE (0.55) | ACEDPP4OPRM1F2PRSS1 | |
| SCHEMBL7402735 | 0.80 | ACE (0.55) | ACEDPP4OPRM1F2PRSS1 | |
| Sulfuric Acid SCHEMBL7270900 | 0.80 | F2 (0.52) | ACEOPRM1F2PRSS1ACE2 | |
| SCHEMBL31091335 | 0.80 | ACE (0.50) | ACELTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |