Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.60 |
| ▸ | FAP | Q12884 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067758 | 0.90 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL21067756 | 0.90 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL30051426 | 0.89 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14020742 | 0.87 | F2 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8862702 | 0.86 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL29541867 | 0.86 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6092096 | 0.86 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6933624 | 0.86 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14985801 | 0.86 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL30833622 | 0.85 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012165-A1 | PROCESS FOR THE PREPARATION OF N-METHYL-D-PHENYLALANYL-N- 1- 3- (AMINOIMINOMETHYL)AMINO]PROPYL]-3,3-DIFLUORO-2-OXOHEXYL]-L-PROLINAMIDE | Aventis Pharmaceuticals Inc. (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1997035874-A1 | PROCESS FOR THE PREPARATION OF N-METHYL-D-PHENYLALANYL-N-[1-[3-[(AMINOIMINOMETHYL)AMINO]PROPYL]-3,3-DIFLUORO-2-OXOHEXYL]-L-PROLINAMIDE | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-02 | — | — | WO | claimed |