Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388094 | 0.91 | — | — | |
| SCHEMBL5819960 | 0.89 | KIF11 (0.35) | KIF11ADORA1CTSSCTSKRXFP1 | |
| SCHEMBL9567369 | 0.86 | KIF11 (0.33) | KIF11ADORA1CTSSCTSKRXFP1 | |
| SCHEMBL10590618 | 0.86 | KDM4E (0.36) | RXFP1ALDH1A1MAPT | |
| SCHEMBL10592455 | 0.86 | ADORA1 (0.39) | ADORA1ALDH1A1DHODH | |
| SCHEMBL9222722 | 0.83 | ADORA1 (0.35) | KIF11ADORA1RXFP1NPC1RAB9A | |
| SCHEMBL9840560 | 0.82 | KIF11 (0.37) | KIF11ADORA1CTSSCTSKNAAA | |
| SCHEMBL9058461 | 0.81 | ADORA1 (0.43) | KIF11ADORA1CTSSCTSKRXFP1 | |
| SCHEMBL9059293 | 0.81 | KIF11 (0.41) | KIF11ADORA1CTSSCTSKRXFP1 | |
| SCHEMBL5812558 | 0.81 | RXFP1 (0.36) | RXFP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | claimed |
| EP-0642303-B1 | SUBSTITUTED 2-ARYLPYRROLES | BAYER AG (DE) | 2000-08-02 | — | — | EP | disclosed |
| US-5521211-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |
| EP-0642303-A1 | SUBSTITUTED 2-ARYLPYRROLES | BAYER AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024484-A1 | SUBSTITUTED 2-ARYLPYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-09 | — | — | WO | disclosed |
| WO-1993024001-A1 | SUBSTITUTED 2-ARYLPYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-09 | — | — | WO | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |