Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059293 | 0.86 | KIF11 (0.41) | ADORA1KIF11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8072565 | 0.81 | KIF11 (0.36) | ADORA1KIF11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9222722 | 0.81 | ADORA1 (0.35) | ADORA1KIF11ALDH1A1MAPTNPC1 | |
| SCHEMBL9057391 | 0.81 | GRIA2 (0.38) | ADORA1KIF11ALDH1A1RETPTGDR2 | |
| SCHEMBL8994389 | 0.79 | ADORA1 (0.34) | ADORA1KIF11MAPTNPC1RAB9A | |
| SCHEMBL10591696 | 0.79 | KIF11 (0.44) | ADORA1KIF11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10589580 | 0.79 | KIF11 (0.44) | ADORA1KIF11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8994420 | 0.79 | KIF11 (0.44) | ADORA1KIF11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8994415 | 0.77 | ALOX5AP (0.33) | ADORA1KIF11RETGRIA2GRIA4 | |
| SCHEMBL9423468 | 0.73 | KIF11 (0.38) | KIF11ALDH1A1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426948-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods | AMERICAN CYANAMID CO (US) | 1996-05-08 | — | — | EP | disclosed |