SCHEMBL80727

SCHEMBL80727

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1N2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.44
MAPT P10636 6/20 0.44
HSD17B10 Q99714 5/20 0.44
KDM4E B2RXH2 4/20 0.44
CASP1 P29466 3/20 0.44
CASP7 P55210 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
TP53 P04637 2/20 0.44
ALOX15 P16050 2/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
THRB P10828 1/20 0.44
TERT O14746 1/20 0.43
S100B P04271 1/20 0.42
L3MBTL1 Q9Y468 6/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPK1 P28482 3/20 0.41
HPGD P15428 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895860 1.00 ALDH1A1 (0.44) ALDH1A1MAPTHSD17B10KDM4ECASP1
Perchlorate SCHEMBL4952408 0.91 ALDH1A1 (0.41) ALDH1A1MAPTHSD17B10KDM4ECASP1
Perchlorate SCHEMBL31339191 0.91 ALDH1A1 (0.41) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL11820212 0.91 ALDH1A1 (0.49) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL10767525 0.89 AR (0.38) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL21628199 0.88 MAOB (0.47) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL21628241 0.87 MEN1 (0.41) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL29636465 0.87 MEN1 (0.41) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL21683278 0.84 S100B (0.38) ALDH1A1MAPTHSD17B10KDM4ECASP1
SCHEMBL21628237 0.84 MEN1 (0.45) ALDH1A1MAPTTP53HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492359-B2 Near-infrared nerve-sparing fluorophores OREGON HEALTH & SCIENCE UNIVERSITY (US) 2022-11-08 US claimed
US-20210317137-A1 NEAR-INFRARED NERVE-SPARING FLUOROPHORES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2021-10-14 US claimed
US-12613133-B2 Inspection tool and inspection method FUJIFILM CORPORATION (JP) 2026-04-28 US disclosed
US-12436096-B2 Ultraviolet inspection tool and inspection method using a visual indicator FUJIFILM CORPORATION (JP) 2025-10-07 US disclosed
US-12372397-B2 Ultraviolet-sensing member, microcapsule, production method of microcapsule, dispersion liquid for forming ultraviolet-sensing layer, and ultraviolet-sensing kit FUJIFILM CORPORATION (JP) 2025-07-29 US disclosed
EP-4317361-B1 TEST TOOL AND TESTING METHOD FUJIFILM CORP (JP) 2025-01-29 EP disclosed
US-20240280405-A1 INSPECTION TOOL AND INSPECTION METHOD FUJIFILM CORPORATION (JP) 2024-08-22 US disclosed
EP-4317361-A1 TEST TOOL AND TESTING METHOD FUJIFILM Corporation (JP) 2024-02-07 EP disclosed
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
EP-4299690-A1 UV RADIATION SENSITIVE MEMBER AND UV RADIATION SENSITIVE KIT FUJIFILM Corporation (JP) 2024-01-03 EP disclosed
US-20230417658-A1 INSPECTION TOOL AND INSPECTION METHOD FUJIFILM CORPORATION (JP) 2023-12-28 US disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0113151-B1 PRINTING MEDIUM AND USE THEREOF International Business Machines Corporation (US) 1988-03-09 EP disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4271251-A LEUCO DYE, PHOTOOXIDIZER, 2,4-DIHYDROXY-BENZALDOXIME FUJI PHOTO FILM CO., LTD. (JP) 1981-06-02 US disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed
US-4090877-A COLOR PHOTOGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492359-B2 Near-infrared nerve-sparing fluorophores NTRK1, PMP22, GAP43 ALDH1A1 813/4885MAPT 636/4885HSD17B10 1810/4885
US-12613133-B2 Inspection tool and inspection method TAS2R30, TAS2R60, TAS2R39 ALDH1A1 910/4885MAPT 1113/4885HSD17B10 3979/4885
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT KIT, SARS1, UNG ALDH1A1 1641/4885MAPT 3053/4885HSD17B10 3235/4885
US-20210317137-A1 NEAR-INFRARED NERVE-SPARING FLUOROPHORES NTRK1, NGF, SMN1; SMN2 ALDH1A1 822/4885MAPT 803/4885HSD17B10 2154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.