Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 18/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 18/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 17/20 | 0.48 |
| ▸ | CDK2 | P24941 | 17/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 17/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | MGMT | P16455 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981045 | 0.90 | CDK1 (0.57) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8075242 | 0.90 | CDK1 (0.57) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL4428837 | 0.90 | CDK1 (0.57) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8076767 | 0.87 | CDK1 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6263155 | 0.73 | CA2 (0.37) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6399589 | 0.69 | CA2 (0.43) | — | |
| SCHEMBL6399587 | 0.69 | CA2 (0.43) | — | |
| SCHEMBL10471471 | 0.68 | CCNK (0.38) | CDK2 | |
| SCHEMBL8069356 | 0.67 | CDK1 (0.69) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL5201806 | 0.67 | CDK1 (0.65) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017394-A1 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-07-12 | — | — | EP | claimed |
| WO-1999002162-A9 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RES CAMPAIGN TECH (GB) | 1999-07-29 | — | — | WO | claimed |
| WO-1999002162-A1 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-01-21 | — | — | WO | claimed |
| EP-1017394-A1 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999002162-A1 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-01-21 | — | — | WO | disclosed |