Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070663 | 0.93 | MMP13 (0.53) | MMP13NAMPT | |
| SCHEMBL8065810 | 0.91 | MMP13 (0.50) | MMP13 | |
| SCHEMBL8066709 | 0.87 | MMP13 (0.49) | MMP13 | |
| SCHEMBL8072435 | 0.87 | MMP13 (0.49) | MMP13 | |
| SCHEMBL3808476 | 0.85 | MMP13 (0.56) | MMP13 | |
| SCHEMBL3808479 | 0.85 | MMP13 (0.56) | MMP13 | |
| SCHEMBL8071946 | 0.85 | MMP13 (0.55) | MMP13 | |
| SCHEMBL8069457 | 0.84 | MMP13 (0.54) | MMP13 | |
| SCHEMBL8068891 | 0.84 | MMP13 (0.61) | MMP13 | |
| SCHEMBL8065798 | 0.84 | MMP13 (0.53) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |