Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388287 | 0.92 | CNR1 (0.45) | CNR1EPHX2 | |
| SCHEMBL8059173 | 0.91 | CYP2C9 (0.44) | NPY1RNPY5RCNR1MEN1KMT2A | |
| SCHEMBL1718512 | 0.90 | NPY1R (0.42) | NPY1RNPY4RNPY5RCNR1 | |
| SCHEMBL6899868 | 0.90 | NPY1R (0.42) | NPY1RNPY4RNPY5RTPSAB1CNR1 | |
| SCHEMBL7059809 | 0.90 | NPY1R (0.42) | NPY1RNPY4RNPY5RTPSAB1CNR1 | |
| SCHEMBL8059066 | 0.90 | CNR1 (0.47) | NPY1RCNR1MEN1KMT2A | |
| SCHEMBL8069325 | 0.90 | CNR1 (0.39) | NPY1RTPSAB1CNR1 | |
| SCHEMBL8527114 | 0.89 | NPY1R (0.41) | NPY1RNPY4RNPY5RTPSAB1MEN1 | |
| SCHEMBL8069613 | 0.88 | PLAAT3 (0.38) | NPY1RNPY5RCNR1EPHX2 | |
| Hydrochloric Acid SCHEMBL8069315 | 0.87 | NPY1R (0.43) | NPY1RNPY4RNPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | claimed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |