Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058871 | 0.92 | ALDH1A1 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL1388287 | 0.91 | CNR1 (0.45) | CNR1EPHX2F10PRSS1CNR2 | |
| SCHEMBL8068045 | 0.90 | EPOR (0.43) | EPOR | |
| SCHEMBL1718512 | 0.90 | NPY1R (0.42) | CNR1NPY5RNPY1RCNR2 | |
| SCHEMBL8069325 | 0.89 | CNR1 (0.39) | CNR1NPY1RF10PRSS1CNR2 | |
| SCHEMBL8059066 | 0.89 | CNR1 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL8073040 | 0.88 | NPY1R (0.41) | CNR1NPY5REPHX2NPY1R | |
| SCHEMBL8070260 | 0.88 | FOLH1 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL8069355 | 0.86 | CNR1 (0.47) | CNR1EPHX2F10PRSS1CNR2 | |
| SCHEMBL9194825 | 0.86 | ALDH1A1 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | claimed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |