Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081105 | 0.79 | SMN1; SMN2 (0.48) | L3MBTL1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL17450551 | 0.78 | KDM4E (0.41) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL7996974 | 0.77 | KMT2A (0.38) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL17450552 | 0.77 | GPR35 (0.40) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL19175805 | 0.75 | CYP1A2 (0.44) | L3MBTL1MEN1KMT2AKDM4EMCL1 | |
| SCHEMBL13982981 | 0.75 | L3MBTL1 (0.38) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL3496090 | 0.75 | MCL1 (0.40) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL3400738 | 0.75 | MEN1 (0.43) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL23235966 | 0.72 | MEN1 (0.36) | L3MBTL1MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL12740595 | 0.72 | HTT (0.55) | L3MBTL1MEN1KMT2AKDM4EMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012252-A1 | AMINOALKYLAZOLE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |