Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789696 | 0.82 | JAK2 (0.48) | KDM4EL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL24800585 | 0.79 | MAPT (0.44) | KDM4EL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL10274687 | 0.75 | PI4KA (0.64) | PI4KAPIK3CGMAPTFYNLRRK2 | |
| SCHEMBL789670 | 0.74 | PI4KA (0.51) | KDM4EALDH1A1MAPK1GAAPI4KA | |
| SCHEMBL20392769 | 0.73 | AKR1C3 (0.51) | NPC1RAB9ACNR2PDE3BPDE3A | |
| SCHEMBL790542 | 0.72 | SRC (0.49) | KDM4EL3MBTL1ALDH1A1GAAPIK3CG | |
| SCHEMBL29964098 | 0.72 | CNR2 (0.50) | KDM4EL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL807327 | 0.71 | HPGD (0.53) | ALDH1A1NPC1RAB9AHPGDMAP2 | |
| SCHEMBL807273 | 0.71 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1PI4KAPIK3CGNPC1 | |
| SCHEMBL790083 | 0.71 | PTGS2 (0.51) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |