Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | MTOR | P42345 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807328 | 0.82 | KDM4E (0.53) | FYNPIK3CGPI4KAKDM4EL3MBTL1 | |
| SCHEMBL789670 | 0.82 | PI4KA (0.51) | FYNPIK3CGPI4KAKDM4EMAPT | |
| SCHEMBL14320480 | 0.81 | JAK2 (0.55) | JAK2FYNPIK3CGMAPTALDH1A1 | |
| SCHEMBL790788 | 0.80 | NPC1 (0.54) | JAK2NPC1RAB9A | |
| SCHEMBL789721 | 0.79 | MAPK14 (0.51) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL807273 | 0.79 | ALDH1A1 (0.53) | JAK2PIK3CGPI4KAL3MBTL1ALDH1A1 | |
| SCHEMBL10274687 | 0.77 | PI4KA (0.64) | JAK2FYNPIK3CGPI4KAMAPT | |
| SCHEMBL791199 | 0.77 | RAB9A (0.50) | JAK2PIK3CGPI4KARAB9APIK3CA | |
| SCHEMBL14320394 | 0.77 | AGXT (0.56) | JAK2PIK3CGMAPTSMN1; SMN2PIK3CA | |
| Formic Acid SCHEMBL790534 | 0.76 | ALDH1A1 (0.50) | JAK2PIK3CGPI4KAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |